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主营:血管内皮生长因子-C, Spp1, IRF-3, DPYSL2, GLUT5
℡ 4000-520-616
℡ 4000-520-616
IBL/Unacylated Ghrelin (dog) Easy Sampling ELISA/CMA05320/
产品编号:CMA05320
市  场 价:¥0.00
场      地:美国(厂家直采)
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:待定
品      牌: IBL
公      司:IBL,inc
公司分类:
IBL/Unacylated Ghrelin (dog) Easy Sampling ELISA/CMA05320/
商品介绍
Kit size12 x 8
MethodELISA
Incubation time1 x 1 h, 1 x overnight at 4°C, 1 x at RT
Standard range2-250 pg/mL
Specimen / Volumes100 µL
Substrate / isotopeER 405-414 nm
Regulatory Status:For research use only
Details for:  Unacylated Ghrelin (dog) Easy Sampling ELISA
This EIA so called Easy Sampling EIA kit works with any sample collected on any kind of protease inhibitors, without extraction but a simple dilution. Ghrelin discovered in 1999, is fast becoming an endocrinology target of the millennium. Ghrelin, identified in rat stomach as an endogenous ligand for the GH secretagogue receptor, is mainly produced in stomach, but has been demonstrated in many other organs. In addition to GH-releasing properties and its orexant action, Ghrelin could act as an hormone having effects on gastric motility (similarity with the peptide hormone motilin), acidic secretion, cardiovascular action, antiproliferative effects, pancreatic and glucose metabolism function, sleep... Ghrelin gene raises to mRNA prepro-ghrelin of 117 amino acids. This precursor is processed into Ghrelin, 28 amino acids (human). Before being secreted, this peptide is octanoylated at Ser 3 by GOAT (Ghrelin Octanoyl Acyl Transferase). This step is essential for biological activity making GOAT a perfect target for drugs in feeding behaviour. Interestingly, the potential therapeutic importance of this hormone is not restricted to regulation of food intake but also in cachexia (related to cancer treatment, anorexia nervosa or ischemia) gastric motility and may be involved in osteoporosis, somatopause, infertility and ovulation induction, neurological disorders (Alcoholism, Post Traumatic Stress disorders...) and cardiovascular diseases.
For concrete data please consult the Instruction for Use in the download box on the right side.
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